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Flinn Lab Activities and Demonstrations
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                 Guided-Inquiry Experiments for General Chemistry, continued
 Separating a Synthetic Pain Relief Mixture— Laboratory Kit
By: The Flinn Staff
Most over-the-counter drugs consist of mixtures, or physical blends, of active drug ingredient(s) and binders. The main characteristic of a mixture is that it has a variable composition—the components of the mixture may be present or mixed in varying proportions. The substances in a mixture retain their distinctive chemical identities, as well as some of their unique physical properties. The purpose of this investigation is to study the physical properties of ingredients in a synthetic pain relief mixture and determine its percent composition.
The lab begins with an introductory activity to test the solubility of each possible component in an organic solvent, ethyl acetate, and in a basic aqueous solution of sodium bicarbonate. The results provide a model for the guided-inquiry design of a flow chart that will map the procedure used to separate components in a mixture and determine percent composition. Optional extension activities include varying the amounts of individual components in the synthetic mixtures and analyzing consumer samples. Students may also measure the melting points of the isolated components, acetylsalicylic acid and acetaminophen, to confirm their identity.
This inquiry lab enforces understanding of solubility and chemical reactions as students carry out their own step-by-step experiments and work collaboratively with their peers.
Complete for 24 students working in pairs.
Separation of a Dye Mixture Using Chromatography— Laboratory Kit
By: The Flinn Staff
The entire palette of artificial food colors is derived from just seven dyes certified by the FDA for use in food, drugs and cosmetics. How can these FD&C dyes be identified in a mixture? How do the molecu- lar structures of the dye molecules influence their properties, relative solubility or affinity for different solvents? The purpose of this guided inquiry lab is to investigate the factors that influence the separation of food dyes using paper chromatography.
The investigation begins with a baseline activity in which students compare the separation or resolution of three FD&C dyes using two solvents. Reviewing the evidence provided by the cooperative class data leads students to select a solvent for further study. In the guided-inquiry section of the lab, students design an experiment to identify a solvent that will give maximum resolution of a mixture of dyes. The results may be applied to study the connection between the structure and mobility of the food dyes. An investigation into the composition of colored candy shells may be incorporated into optional extension activities.
The primary learning objectives for this inquiry lab focus on the effects of molecular structure on the nature and strength of intermolecu- lar forces between molecules or ions. The lab also integrates key science practice skills for analyzing data to identify trends.
Complete for 24 students working in pairs.
Separating a Synthetic Pain Relief Mixture—Laboratory Kit AP7980
  Guided-Inquiry Experiments for General Chemistry—16-Kit Bundle
Save by ordering the complete Guided-Inquiry Experiments for General Chemistry—16-kit bundle! Comprehensive, cost-
saving bundle includes all 16 of the kits on pages 15–20.
 Catalog No.
  Description
  Price/Each
   AP7983
 Guided-Inquiry Experiments for General Chemistry—16-Kit Bundle
   $862.00
   Catalog No.
  Description
  Price/Each
   AP7980
 Separating a Synthetic Pain Relief Mixture—Laboratory Kit
   $65.75
  Separation of a Dye Mixture Using Chromatography—Laboratory Kit AP7981
 Catalog No.
  Description
  Price/Each
   AP7981
 Separation of a Dye Mixture Using Chromatography—Laboratory Kit
   $61.15
 


























































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