Publication No. 10686
“Constructing” Mitosis the 5E Way
Student Laboratory Kit
Materials Included In Kit
Additional Materials Required
Beakers or other containers
Although the materials in this activity are considered non-hazardous, please follow all normal laboratory safety procedures.
Enough materials are provided in this kit for 30 students working in pairs or for 15 groups of students.|The Engage, Explore and Explain sections can reasonably be completed in one 50-minute class period. The Elaborate and Evaluate sections will require at least one additional day, depending on the level of the class.|Answers to the questions in the Explore section should be discussed before students move on to the Explain section. Doing so will help them understand the simulation better.|The Elaborate section should not be given to any student group until the Engage, Explore and Explain sections have been completed and discussed. If several groups are lagging behind the others, assign groups that are finished to help them.|A compound microscope should be available for student use in the Evaluate section. Whitefish blastula slides may be used in addition to onion root tips for a comparison of plant and animal cell mitosis.
Correlation to Next Generation Science Standards (NGSS)†
Science & Engineering PracticesDeveloping and using models
Disciplinary Core IdeasMS-LS1.A: Structure and Function
HS-LS1.B: Growth and Development of Organisms
Crosscutting ConceptsSystems and system models
Structure and function
MS-PS1-2: Analyze and interpret data on the properties of substances before and after the substances interact to determine if a chemical reaction has occurred.
Answers to Questions
Use a textbook and/or the Internet to answer Questions 1–4.
Prophase, Metaphase, Anaphase, Telophase
Prophase—the nuclear membrane disappears, chromosomes become more visible
A cell’s chromosomes are replicated (copies are made) so that each new cell has an exact copy of the original chromosomes.
Mitosis is necessary so that every cell, when it divides, reproduces new “daughter” cells with the exact same number and kind of chromosomes that were present in the original cell.
Two new “daughter” cells that are identical to the original cell in terms of number and kind of chromosomes present.
Asexual reproduction does not involve the exchange and mixing of the genetic information from the parents. Therefore, the offspring of asexually-reproducing organisms are clones of the parent organism. Mitosis produces two exact copies or clones, of the original cell.
Letter e would be correct because growth is due to an increase in the number of cells and mitosis is the process that causes growth. Letter a could also be correct if the response to a stimulus was, for example, the healing of the skin after a cut. Letter b could also be correct if an organism reproduces asexually, without producing sex cells (gametes).
“Constructing” Mitosis the 5E Way
As we grow or when we sustain any kind of injury to our skin, bones, etc., the process of growing and healing always involves an increase in the number of individual cells. How does this happen? By constructing simplified, simulated cells containing chromosomes, mitosis (asexual reproduction) and cytokinesis (division of the cytoplasm), the process will be more fully understood.
A Doritos® corn chip commercial once stated, “Crunch all you want, we’ll make more!” Imagine that one day, while munching and crunching a snack-size bag of Doritos outside your house, a good friend shows up. What would you do? (Circle one answer.)
Chalk, 1 piece
Student Worksheet PDF