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360Storylines—Curing Disease, 1-Year Access

By: The Flinn Scientific Staff

Item #: AP11000

Price: $275.00

In Stock.

Use the 4 labs in this 360Storyline to lead students to a written understanding/working model of how scientists learn about the structure and function of cells ultimately lead to medical advances.

 

Key Concepts

  • Semipermeable Plasma Membrane
  • Diffusion/Osmosis
  • Enzyme Catalyzed Reactions
  • Tissue Regeneration
  • Cell Cycle and Disease
  • Bioinformatics
  • Phylogeny
  • Protein Structure

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This item can only be shipped to schools, museums and science centers

Product Details

360Storyline is a collection of experiments that together let students engage in science in an authentic manner through the use of relevant phenomena. Each experiment in a 360Storyline builds on things learned in the preceding experiments until students develop a final, working explanation or model of the phenomenon. Every lab in any 360Storyline is completely editable and supported by videos and simulations. 

Includes:

  • Access to digital content for 1 year
  • Lab supplies for each experiment for a single class of 30 students

 

Curing Disease
Lead students to a written understanding/working model of how scientists learn about the structure and function of cells ultimately lead to medical advances. Students are introduced to techniques, tools and modern bioinformatics methods used by professionals in the field. With intimate knowledge of the metabolic functioning of cells (e.g., how molecules cross semipermeable membranes, the role enzymes play in our bodies and their limitations, the regenerative properties of some cells, how the cell cycle can malfunction) and the evolutionary path of proteins, comes hope for new discoveries to comfort and cure the diseased. A great example for exploring the curing of disease is to learn how science plays a role in driving medical technology and practices.

What Students Do

Lab 1—Cell Membrane Permeability
Students observe the movement of the vital stain, neutral red, across the phospholipid membranes of yeast cells. Students then determine how the environmental conditions under which cells exist can impact the movement of molecules across a semipermeable membrane.

Lab 2—Water Potential
Students explore water potential as they expose plant cells to altered dilution ratios (solute/solvent ratios) outside the cell.

Lab 3—Peroxidase Enzyme Activity
Students experiment with the importance of enzyme-catalyzed biochemical reactions and how altering the environment of cells can change enzyme efficacy.

Lab 4—Planaria Regeneration
Students observe flat-bodied worms, Planaria, for their behavior and carry out an investigation to determine their tissue regenerative properties.

Lab 5—Cancer and the Loss of Cell Cycle Control
Students explore the consequences of uncontrolled cell division. They explore how scientists use karyotyping to detect chromosomal errors associated with cancer and other diseases.

Lab 6—Understanding Evolutionary Relationships
Students become familiar with bioinformatics—the interdisciplinary field of science that integrates biology, computer sciences, software tools, databases, information engineering, mathematics and statistics. Students explore the National Center for Biotechnology Information website and utilize BLAST (Basic Local Alignment Search Tool) to investigate the conservation of specific proteins when comparing various eukaryotic organisms.

About 360Storylines

360Storyline is a collection of experiments that together let students engage in science in an authentic manner through the use of relevant phenomena. Each experiment in a 360Storyline builds on things learned in the preceding experiments until students develop a final, working explanation or model of the phenomenon. Every lab in any 360Storyline is completely editable and supported by videos and simulations. 

Students must drive the learning forward by developing procedures and asking questions. Each storyline is supported by editable documents that force students to think about how the data they collect relate to an individual experiment’s investigative phenomenon and how the data they collect in a series of labs relate to a broader, anchoring phenomenon.

Specifications

1-Year Access


Correlation to Next Generation Science Standards (NGSS)

Science & Engineering Practices

Developing and using models
Planning and carrying out investigations
Engaging in argument from evidence
Obtaining, evaluating, and communicating information

Disciplinary Core Ideas

HS-LS1.A: Structure and Function
HS-LS1.B: Growth and Development of Organisms
HS-LS3.B: Variation of Traits
HS-LS4.A: Evidence of Common Ancestry and Diversity

Crosscutting Concepts

Systems and System Models
Stability and Change of Systems
Cause and Effect
Patterns

Performance Expectations

HS-LS1-2: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
HS-LS1-3: Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis.
HS-LS1-4: Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms.
HS-LS3-2: Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.
HS-LS4-1: Communicate scientific information that common ancestry and biological evolution are supported by multiple lines of empirical evidence.