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Antibody Function—Student Laboratory Kit

By: William P. Baker, PhD. Western Kentucky Community and Technical College, Paducah, KY

Item #: FB1967

Price: $18.75

In Stock.

In the Antibody Function and Epidemiology Laboratory Kit for biology and life science, construct an antibody model by selecting from a variety of possible heavy and light chain regions to form an IgG antibody.

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Product Details

The human body is constantly exposed to microbes, toxins, dust and pollen—foreign substances that are potentially harmful and may cause disease. One of the most important defenses the body uses to fight these foreign antigens is the production of antibodies. In this simulation of antibody diversity and antibody–antigen binding; students construct an antibody model by selecting from a variety of available heavy and light chain regions possibilities to form an IgG antibody. They then investigate binding of their unique antibody with different antigen templates to determine if there is a match. Students subsequently understand the fate of their constructed antibody based upon it finding or not finding a matching antigen. Activity provides a creative way to identify “lock-and-key” biological relationships. This kit includes enough antibody models for 30 students working individually, two shared copies of each simulated antigen, detailed background information and procedures, as well as reproducible student worksheets and valuable Teacher Notes.

Specifications

Materials Included in Kit: 
Antibody regions model sheet, 30
Antigen template


Correlation to Next Generation Science Standards (NGSS)

Science & Engineering Practices

Developing and using models
Engaging in argument from evidence

Disciplinary Core Ideas

HS-LS1.A: Structure and Function

Crosscutting Concepts

Patterns
Systems and system models
Structure and function

Performance Expectations

HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.