Teach students to identify and classify chromosome smears according to the Denver System using large magnetic demonstration models of chromosomes! Begin by building a karyotype of a normal male and a normal female on your magnetic classroom board. Investigate the karyotypes of eight different chromosomal abnormalities. These conditions include Down’s Syndrome (Trisomy 21), Edward’s Syndrome (Trisomy 18), Patau Syndrome (Trisomy 13), Klinefelter’s Syndrome, Disomy Y, Triple X (Trisomy X), Turner Syndrome (Monosomy X) and Robertson Translocation. Kit contains one 12" × 36" magnet with copies of all chromosomes necessary to perform this demonstration. Chromosomes may easily be cut from the magnet using a paper cutter and/or scissors.
Concepts: Chromosome smear, karotyping, chromosonal abnormalities, homologous chromosomes. Time Required: One class period Materials Provided: Denver System Template, magnetic chromosomes.