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Virulence: An Infectious Card Game is a blind bidding game for biology in which players take on the roles of viruses competing to infect a host cell.

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Virulence is a blind bidding game in which players take on the roles of viruses competing to infect a host cell. Players use their bidding hands to win (replicate) viral component cards in order to either score points or build the strength of their virus (their bidding hand) increasing their odds of winning critical bids later in the game. Virulence complies with NGSS standards and STEM principles. Gameplay takes approximately 20 minutes and accommodates 2–5 players.