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Disposable Dialysis Tubing Clamps are inexpensive and actually work. Package of 100 clamps.

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Finally, an inexpensive dialysis tubing clamp that works! Just twist the end of the wet dialysis tubing a few times, place the clamp over the twisted area, and squeeze the vise-like clamp together. It will not pull off nor will any molecules diffuse through the clamped area. Dispose of the clamps along with the used dialysis tubing. Package of 100 clamps.