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Biotechnology Introductory Kits
99
Biotechnology—Introductory Kits, continued
DNA and Electrophoresis Simulation—
Super Value Kit
By: Sue Whitsett
Fond du Lac High School, Fond du Lac, WI
A fun kinesthetic way to teach DNA structure and restriction enzymes. Every student in your class becomes a coded nucleotide, and together the entire class will form a giant DNA molecule. Students will person- ally experience the antiparallel and coding structure of DNA. Once built, the giant DNA molecule is cut by a restriction enzyme. Then the challenge for each DNA fragment team is to run an obstacle course simulating gel electrophoresis. This DNA activity will be remembered! A Flinn workshop favorite! Includes base pair connecting rods and complete teaching instructions.
Super Value Kit is complete for 30 students. All materials are reusable.
See free video at flinnsci.com.
Gel Electrophoresis Simulation—
Super Value Kit
By: The Flinn Staff
This pop bead simulation will help students visualize how the sepa- ration of molecular fragments occurs during gel electrophoresis. This involving set of materials is a great precursor to actual electro- phoresis work. Students build models of DNA fragments with pop beads and then place them on a paper simulated agarose gel. Based upon the fragment length and migration distance, students calcu- late the Rf values and draw a standard curve plot for their sample. From the standard curve plot they can deduce the length of an unknown fragment. Includes over 600 pop beads. The provided masters allow students to complete the standard curve plots individually. Six different sets of fragment data are provided so that student groups can be working on different samples during the lab.
Super Value Kit is complete for 30 students working in pairs. All materials are reusable.
A Case of Abduction—
DNA Identity Testing Simulation
By: William Humphries
Richardson H.S., Richardson, TX
A reality-based exploration into identity testing using mitochondrial DNA analysis. Your students play the role of investigators in an abduc- tion case. The fascinating and highly educational simulation combines elements of history, human rights, family impact, forensic science, and genetics.
In the course of their investigation, students will:
• “Digest” short, 60 base-pair sequences of mitochondrial DNA using
Hae III restriction enzyme.
• Determine the sizes of the resulting “fragments” and use a standard
curve to plot the migration distance for each fragment on a paper
“gel”.
• Label the separated fragments with a “radioactive probe sequence”.
• Interpret the results to determine the true parentage of a child alleg-
edly abducted as an infant.
Includes extensive background information, objectives, reproducible student copy masters, detailed results, study and follow-up questions, glossary, and extension ideas. The activity is designed to be conducted by cooperative teams and can be completed in two class periods.
DNA and Electrophoresis Simulation—Super Value Kit FB1228
Catalog No.
Description
Price/Each
FB1228
DNA and Electrophoresis Simulation—Super Value Kit
$59.40
Catalog No.
Description
Price/Each
FB1434
Gel Electrophoresis Simulation—Super Value Kit
$46.55
Gel Electrophoresis Simulation—Super Value Kit FB1434
Catalog No.
Description
Price/Each
FB0506
A Case of Abduction—DNA Identity Testing Simulation
$39.45
BIOTECHNOLOGY—INTRODUCTORY KITS continued on next page.
A Case of Abduction—DNA Identity Testing Simulation FB0506