Gel Electrophoresis Simulation Kit for biotechnology is a pop bead simulation that will help visualize how the separation of molecular fragments occurs during gel electrophoresis. Build models of DNA fragments with pop beads.
This pop bead simulation will help students visualize how the separation of molecular fragments occurs during gel electrophoresis. This involving set of materials is a great precursor to actual electrophoresis work. Students build models of DNA fragments with pop beads and then place them on a paper simulated agarose gel. Based upon the fragment length and migration distance, students calculate the Rf values and draw a standard curve plot for their sample. From the standard curve plot they can deduce the length of an unknown fragment.Over 600 pop beads are included in the kit, enough for 30 students working in pairs. The provided masters allow students to complete the standard curve plots individually. Six different sets of fragment data are provided so that student groups can be working on different samples during the lab.
Correlation to Next Generation Science Standards (NGSS)
Science & Engineering Practices
Analyzing and interpreting data Developing and using models
Disciplinary Core Ideas
MS-PS1.A: Structure and Properties of Matter HS-PS1.A: Structure and Properties of Matter
Crosscutting Concepts
Patterns Scale, proportion, and quantity
Performance Expectations
MS-PS1-1. Develop models to describe the atomic composition of simple molecules and extended structures.
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