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Product 14189

By: The Flinn Staff

In the Plasmid and Genetic Engineering Simulation Kit for biotechnology, manipulate simulated plasmids. Key concepts related to recombinant DNA will be visible and manipulated during this activity.

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“Genetic engineering” is a 20th century reality but is still quite controversial. Making recombinant DNA molecules is at the heart of the “engineering.” Students will simulate an important part of the engineering process as they manipulate simulated plasmids. Following specific restriction enzyme cuts in their plasmid models, they consider all of the possible recombination patterns that can result from their plasmid pieces. All of the combinations represent potential newly-engineered plasmids with unique characteristics. The key concepts related to recombinant DNA will be visible and manipulated by students during this activity. Teacher Notes, reproducible student handouts and over 1,800 colored pop-beads are provided.Complete for 30 students working in pairs.

Correlation to Next Generation Science Standards (NGSS)

Science & Engineering Practices

Developing and using models
Planning and carrying out investigations
Analyzing and interpreting data
Constructing explanations and designing solutions

Disciplinary Core Ideas

MS-LS3.A: Inheritance of Traits
MS-LS1.B: Growth and Development of Organisms
HS-LS1.A: Structure and Function
HS-LS3.A: Inheritance of Traits

Crosscutting Concepts

Patterns
Systems and system models
Structure and function

Performance Expectations

MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.