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Recombinant DNA—Super Value Kit

By: The Flinn Staff

Item #: FB1921

Price: $43.05

In Stock.

In the Recombinant DNA Laboratory Kit for biotechnology, simulate the roles of restriction enzymes and DNA ligase In the formation of recombinant DNA.

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Product Details

Bring microscopic genetic techniques to life size by building a recombinant DNA plasmid! Simulate the roles of restriction enzymes and DNA ligase in the formation of recombinant DNA. Students will construct plasmid DNA using chenille wire and four different colored pony beads—each representing a different nitrogenous base. Students will manipulate the plasmid by locating restriction sites and cutting the chenille wire as the restriction enzyme would do to the plasmid. They will then insert genes of interest using pony beads, and twist the wire back together to simulate ligating the plasmid. Includes a pre-lab, paper-and-pencil activity to familiarize students with the process of forming recombinant DNA molecules before beginning the activity. Complete with enough reusable materials for 30 students working in pairs, or 15 groups of students. Also includes reproducible student handouts as well as complete Teacher Notes.

Specifications

Materials Included in Kit: 
Chenille wires, blue, 12" long, 30
Chenille wires, red, 12" long, 30
Pony bead, blue, 360
Pony bead, green, 500
Pony bead, pink, 360
Pony bead, white, 500
Vinyl twist ties, white, 5", 40


Correlation to Next Generation Science Standards (NGSS)

Science & Engineering Practices

Asking questions and defining problems
Developing and using models
Planning and carrying out investigations
Constructing explanations and designing solutions
Engaging in argument from evidence

Disciplinary Core Ideas

HS-LS1.A: Structure and Function
HS-LS3.A: Inheritance of Traits
HS-LS3.B: Variation of Traits

Crosscutting Concepts

Patterns
Cause and effect
Systems and system models
Structure and function

Performance Expectations

HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
HS-LS3-1. Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.