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The Genetics of Cancer—Student Laboratory Kit

By: The Flinn Staff

Item #: FB1800

Price: $99.50

In Stock.

In The Genetics of Cancer Laboratory Kit, use biotechnology to determine who carries the BRCA-1 and BARD-1 genes for hereditary breast-ovarian cancer (HBOC).

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This item can only be shipped to schools, museums and science centers

Product Details

"You have cancer" has been the most feared phrases for 40 years. "You carry the gene for cancer" has become a very real fear for the last 20 years. In this laboratory kit students use biotechnology to determine who carries the BRCA-1 and BARD-1 genes for hereditary breast-ovarian cancer (HBOC). Students must identify the unique DNA bands that form during gel electrophoresis analysis and compare the bands to see who is a carrier. The four samples of enzyme-restricted DNA are ready to load into student-prepared gels. DNA source is Lambda phage. This kit contains comprehensive background information about germline mutations and DNA analysis plus step-by-step procedures, questions and teacher's notes. Enough materials are supplied to run six gels. Required electrophoresis apparatus and power supply. The DNA contained in this kit must be kept frozen prior to use. Orders will only be shipped between September 15 and May 15 unless we are told otherwise. Upon receipt, this kit should be stored in the freezer until just before it is to be used.


Materials Included in Kit: 
Agarose, LE, 3 g
DNA samples and practice pipetting solution, kept in freezer
Electrophoresis buffer, concentrated 50x, 100 mL
Methylene blue electrophoresis stain, 10x, 100 mL
Pipets, needle tip, disposable, 30
Weighing dish, disposable, 5.5 g, 5.5" x 5.5", 6

Correlation to Next Generation Science Standards (NGSS)

Science & Engineering Practices

Analyzing and interpreting data
Developing and using models
Constructing explanations and designing solutions

Disciplinary Core Ideas

MS-LS1.B: Growth and Development of Organisms
HS-LS1.B: Growth and Development of Organisms
HS-LS1.A: Structure and Function
HS-LS3.A: Inheritance of Traits

Crosscutting Concepts

Cause and effect
Structure and function

Performance Expectations

MS-LS3-2: Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation.
HS-LS1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.